Good to see you're using the equity in your home to further your own wealth and best of luck with the journey.
You can set up two accounts but there's really no need. In some cases (say with St George) you can set up a single line of credit (Portfolio account) and have several sub-accounts under it. Best to have these set as I/O (and capitalising if you wish), while continue to put your remaining capital into your PPOR.